What Is Co Amoxiclav Used For?
- 1 When should Amoxiclav be taken?
- 2 How fast does Amoxiclav work?
- 3 What should I avoid while taking AMOX CLAV?
- 4 Can Amoxiclav make you tired?
- 5 Is 5 days of antibiotics enough?
- 6 How do you know if antibiotics are working?
- 7 Is it OK to take Amoxiclav twice a day?
Is Amoxiclav a strong antibiotic?
How does co-amoxiclav work? – The amoxicillin part of co-amoxiclav works by interfering with the ability of bacteria to form cell walls. It allows holes to appear in the bacterial cell walls and this kills the bacteria causing the infection. Some types of bacteria have become resistant to penicillin-type antibiotics, because they have developed the ability to produce defensive chemicals called beta-lactamases that stop the antibiotics from working.
- The clavulanic acid part of co-amoxiclav is a beta-lactamase inhibitor.
- It stops bacteria from inactivating the amoxicillin, so increases the range of bacteria that amoxicillin can kill.
- Co-amoxiclav is a broad-spectrum antibiotic, which means it can treat infections caused by a wide variety of bacteria.
However, it does not kill viruses and will not work to treat viral infections, such as colds, flu and most coughs and sore throats. It’s usually reserved for treating infections caused by bacteria that are resistant to amoxicillin. To make sure the bacteria causing an infection are susceptible to co-amoxiclav, your doctor may take a tissue sample, for example a swab from the throat or skin, or a urine or blood sample.
What is Amoxiclav prescribed for?
Descriptions – Amoxicillin and clavulanate combination is used to treat bacterial infections in many different parts of the body (eg, ear, lungs, sinus, skin, urinary tract). Amoxicillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors.
- Tablet, Chewable
- Powder for Suspension
- Tablet, Extended Release
When should Amoxiclav be taken?
Dosage – The usual dose of co-amoxiclav is 1 tablet (either 375mg or 625mg) taken 3 times a day. The dose may be lower for children. The doctor will use your child’s weight to work out the right dose of the liquid for them. Try to space the doses out evenly throughout the day, at least 4 hours apart.
Why is co-amoxiclav not recommended?
Who may not be able to take co-amoxiclav – Co-amoxiclav is not suitable for some people. To make sure it’s safe for you, tell your doctor if you:
have ever had an allergic reaction to amoxicillin, clavulanic acid, penicillin or any of the other ingredientshave ever had a severe allergic reaction to any other antibiotic – this can include a skin rash or swelling of the face and throathave ever had liver problems or (yellowing of the whites of the eyes or the skin) when taking antibioticshave (or think you may have) have liver or kidney problemshave a rare inherited condition called – co-amoxiclav liquid may contain aspartame, which can be harmful if you have this conditionare not peeing regularly
Page last reviewed: 21 September 2022 Next review due: 21 September 2025 : Who can and cannot take co-amoxiclav
How fast does Amoxiclav work?
Amoxicillin fights infections in the body within an hour after taking it. The penicillin-based medication gets its strength from consistent use of multiple doses per day. Amoxicillin often relieves symptoms in less than 72 hours and stays in your system for 24 hours.
How long does it take for Amoxiclav to start working?
Key facts –
For most infections, you’ll start to feel better within a few days.Usually, you take co-amoxiclav 3 times a day.The most common side effects of co-amoxiclav are diarrhoea, thrush and feeling or being sick.Co-amoxiclav liquid can stain teeth. This is not permanent and brushing your teeth will remove any stains.It’s best to avoid alcohol if the medicine makes you feel sick. Drinking large amounts could also make you more likely to get side effects of co-amoxiclav affecting your liver.
Page last reviewed: 21 September 2022 Next review due: 21 September 2025
What should I avoid while taking AMOX CLAV?
The bottom line. Amoxicillin/clavulanate is an antibiotic medication used to treat bacterial infections. It can interact with warfarin, alcohol, and gout medications. Some data has suggested it can interact with birth control pills, but this doesn’t appear to be true.
What infections does Amoxiclav treat?
Co-amoxiclav side effects & other co-amoxiclav info
|Make sure you tell your doctor if you are allergic to penicillin. Co-amoxiclav is a type of penicillin – do not take it if you are allergic to penicillin. Space your doses out evenly over the day and complete the full course of this antibiotic, even if you feel your infection has cleared up. You can take co-amoxiclav before or after food. If you have an allergic reaction (such as any swelling around your mouth, any difficulties breathing or a red rash) contact a doctor for advice straightaway.
Co-amoxiclav is given to treat bacterial infections. It is prescribed for sinus infections, urine infections, skin infections, joint infections and some dental infections. It is also given before some surgical operations, to prevent an infection from developing.
- Co-amoxiclav contains two ingredients, amoxicillin and clavulanic acid.
- The first ingredient, amoxicillin, is a penicillin antibiotic which treats infection by killing the bacteria responsible for the infection.
- Some bacteria are able to produce a chemical which makes amoxicillin less effective.
- The second ingredient, clavulanic acid, stops this from happening.
Clavulanic acid stops the chemical produced by the bacteria from working, and this allows the amoxicillin to kill the bacteria. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.
If you suspect you may have glandular fever.If you have an allergic condition, or if you have ever had an allergic reaction to a medicine. This is especially important if you have ever had a bad reaction to any penicillin antibiotic.If you are pregnant or breastfeeding. Co-amoxiclav is not known to be harmful to babies; however, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.If you have any problems with the way your liver works, or problems with the way your kidneys work.If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give you more information about co-amoxiclav and will provide you with a full list of the side-effects which you may experience from taking it.Take co-amoxiclav exactly as your doctor tells you to. It is usually taken three times daily, every eight hours. It is important that you space out the doses evenly during the day. Your doctor or pharmacist will tell you how many tablets (or how much liquid medicine) to take for each dose, and this information will be printed on the label of the pack to remind you. If you have been given liquid medicine for a child, read the directions carefully to make sure you measure out the correct amount of medicine.Try to drink plenty of water while you are taking co-amoxiclav, to help keep your kidneys working well. You can take your doses before or after food.If you forget to take a dose, take one as soon as you remember. Try to take the correct number of doses each day, but do not take two doses at the same time to make up for a forgotten dose.
If you (or your child) have been prescribed the oral liquid medicine, you may find that it causes some staining of the teeth. This will disappear soon after the course of antibiotics is finished.Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished, unless you are told to stop. This is to prevent the infection from coming back. Your doctor will tell you how long your course of treatment will last – this is not usually for longer than 14 days. If you still feel unwell after finishing the course, go back to see your doctor.Some people develop redness and itching in the mouth or vagina (thrush) after taking a course of antibiotics. If this happens to you, speak with your doctor or pharmacist for advice.If you are taking the contraceptive ‘pill’ at the same time as this antibiotic, the effectiveness of the ‘pill’ can be reduced if you have a bout of being sick (vomiting) or diarrhoea which lasts for more than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the next few days. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours.Co-amoxiclav may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this antibiotic.
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with co-amoxiclav. You will find a full list in the manufacturer’s information leaflet supplied with your medicine.
|Very common co-amoxiclav side-effects (these affect more than 1 in 10 people)
|What can I do if I experience this?
|Drink plenty of water to replace any lost fluids. If the diarrhoea continues, becomes severe, or contains blood, let your doctor know straightaway
|Common co-amoxiclav side-effects (these affect fewer than 1 in 10 people)
|What can I do if I experience this?
|Feeling sick (nausea) or being sick (vomiting)
|You can reduce this by taking your doses at a mealtime
|Redness and itching in the mouth or vagina (thrush)
|Speak with your doctor for advice about treatment
Important : if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more co-amoxiclav and speak with your doctor or go to your local accident and emergency department straightaway.
Keep all medicines out of the reach and sight of children.Keep co-amoxiclav liquid medicine in a refrigerator, and do not use it after the expiry date on the bottle. It will have been made up by the pharmacy and it is important you do not store or use it for longer than seven days since the date it was made up.Store co-amoxiclav tablets in a cool, dry place, away from direct heat and light.
|Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines. If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine ask your pharmacist.
Co-amoxiclav side effects & other co-amoxiclav info
How many days do you take AMOX CLAV?
The dosing for amoxicillin/clavulanate (Augmentin) is given based on the milligrams of the amoxicillin. Sinus infection and pneumonia (adults and children who weigh 88 lbs or more): The typical dose is to take 2,000 mg of amoxicillin by mouth every 12 hours for 7 to 10 days.
Can Amoxiclav make you tired?
Frequently Asked Questions – Why do antibiotics have side effects? Antibiotics are powerful medications, and like most medications, they can cause unwanted side effects. These can happen for a variety of reasons, including disrupting the balance of “good” and “bad” bacteria in your body.
- Can you stop fatigue from antibiotics? If you’re feeling tired or sleepy while taking antibiotics, reach out to your doctor who may be able to switch you to a different medication.
- Is tiredness a normal side effect of antibiotics? Tiredness or fatigue is not a common side effect of antibiotic use, but it can happen.
The antibiotics most likely to cause tiredness as a side effect are amoxicillin, azithromycin, and ciprofloxacin. K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. This information does not constitute and should not be relied on for professional medical advice.
Can I take Amoxiclav and paracetamol at the same time?
No interactions were found between amoxicillin / clavulanate and Paracetamol.
Is Amoxiclav safe to take?
Co-amoxiclav is generally a safe drug. However, it sometimes has serious side effects.
What bacteria is resistant to co-amoxiclav?
Screening for co-amoxiclav-resistant E. coli isolates in faeces – Stool could be sampled from only 46 (42.6%) of the 108 patients, on average, 3.3 days (0–16 days) after the beginning of the treatment of the UTI. As indicated in Table 1, no Gram-negative bacilli were isolated from the stools of 11 of these 46 patients (24%), whereas 17 (37%) had a Gram-negative flora fully susceptible to co-amoxiclav; 18 (39%) had a Gram-negative flora resistant to co-amoxiclav. For 10 of the latter patients, co-amoxiclav-resistant organisms were E. coli species, and in eight others they were bacterial species inherently resistant to co-amoxiclav, such as Enterobacter spp., Citrobacter freundii and Pseudomonas aeruginosa (data not shown). Overall, 10 of the 46 patients (22%) carried co-amoxiclav-resistant E. coli in their digestive tract. The great majority of patients (41/46) were receiving antibiotic treatment for an E. coli UTI when stool samples were taken (Table 1 ). The most common treatment consisted of third-generation cephalosporins ( n = 20), followed by fluoroquinolones ( n = 9), co-amoxiclav ( n = 6) and amoxicillin ( n = 5) (Table 1 ). Treatment with other antibiotics not active against E. coli was given for a concurrent infection in one case. Among the five patients not receiving antibiotics on the day of stool sampling, one was never treated, and four were treated immediately after specimen collection. Amoxicillin treatment appeared to be a risk factor associated with the isolation of co-amoxiclav-resistant Gram-negative bacilli (RR = 4.29; 95% CI 2.24–8.20; P = 0.002), especially E. coli (RR = 6; 95% CI 2.18–16.51: P = 0.006), in the digestive tract in comparison with all treatments except co-amoxiclav. A similar risk factor was found with co-amoxiclav treatment in comparison with all other treatments except amoxicillin, in terms of isolation of all Gram-negative species resistant to co-amoxiclav (RR = 2.86; 95% CI 1.21–6.76; P = 0.05), but not for the isolation of co-amoxiclav-resistant E. coli alone (RR = 2.5; 95% CI 0.58–10.70; P = 0.26). Treatment with third-generation cephalosporins was associated with the absence of Gram-negative bacilli in the digestive tract in comparison with all other treatments (RR = 4.72; 95% CI 1.16–19.25; P < 0.03) and aminopenicillin treatment ( P < 0.02).
Is 5 days of antibiotics enough?
A duration of 5–7 days of antibiotics is recommended in adults. This is supported by a systematic review showing no significant difference in outcomes between 3–7 days of antibiotics compared to 7 days or longer.16 For children with non-severe pneumonia there is no difference between 3 versus 5 days of antibiotics.
Can Amoxiclav make you feel ill?
If you take too much Co-amoxiclav film-coated tablets, signs might include an upset stomach (feeling sick, being sick or diarrhoea) or convulsions. Talk to your doctor as soon as possible. Take the medicine carton to show the doctor. If you forget to take a dose, take it as soon as you remember.
How many times a day should Amoxiclav be taken?
pronounced as (a mox I sil’ in) Amoxicillin is used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin.
- It is also used in combination with other medications to eliminate H.
- Pylori, a bacteria that causes ulcers.
- Amoxicillin is in a class of medications called penicillin-like antibiotics.
- It works by stopping the growth of bacteria.
- Antibiotics such as amoxicillin will not work for colds, flu, and other viral infections.
Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Amoxicillin comes as a capsule, a tablet, a chewable tablet, and as a suspension (liquid) to take by mouth. It is usually taken every 12 hours (twice a day) or every 8 hours (three times a day) with or without food.
The length of your treatment depends on the type of infection that you have. Take amoxicillin at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amoxicillin exactly as directed.
Do not take more or less of it or take it more often than prescribed by your doctor. Shake the suspension well before each use to mix the medication evenly. The suspension may be placed directly on the child’s tongue or added to formula, milk, fruit juice, water, ginger ale, or another cold liquid and taken immediately.
The chewable tablets should be crushed or chewed thoroughly before they are swallowed. Swallow the tablets and capsules whole with a full glass of water; do not chew or crush them. You should begin to feel better during the first few days of treatment with amoxicillin. If your symptoms do not improve or get worse, call your doctor.
Take amoxicillin until you finish the prescription, even if you feel better. If you stop taking amoxicillin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Amoxicillin also is sometimes used to treat Lyme disease, to prevent anthrax infection after exposure, and to treat anthrax infection of the skin,
How do you know if antibiotics are working?
Frequently Asked Questions – How can you tell if antibiotics are working? Unfortunately, there’s no way to tell if antibiotics are working. Though antibiotics start working as soon as you take them, it can take several days for you to begin feeling the effects.
However, by the end of your recommended course, you should feel a noticeable difference in (or total disappearance of) your symptoms. What is antibiotic resistance? Antibiotic resistance occurs when bacteria have found a way to survive the medication designed to kill it—not when your body has become resistant to antibiotics.
Antibiotic resistance is a growing issue both nationally and internationally, with some bacteria exhibiting resilience to the most powerful antibiotics available. Can you make antibiotics work faster? Unfortunately, there is no way to make antibiotics work faster.
Regardless of your condition or the antibiotic being used, always follow the instructions as provided by your doctor or pharmacist. K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. This information does not constitute and should not be relied on for professional medical advice.
Always talk to your doctor about the risks and benefits of any treatment.
Is it OK to take Amoxiclav twice a day?
The usual adult dose is one 375 mg tablet three times a day or one 625 mg tablet twice a day. For oral suspension, shake the bottle before each use. Take it at the start of meal to reduce stomach upset. Tablets can be cut along the line for easier swallowing.
What antibiotic is stronger than Amoxiclav?
Abstract – Azithromycin, a broad-spectrum azalide, and co-amoxiclav were compared in a randomized, multicentre, open-label trial in 759 patients treated for acute tracheobronchitis (n = 620) or acute infectious exacerbations of chronic bronchitis (n = 139).
- Patients were randomized (2:1) to a 3-day regimen of two azithromycin 250 mg capsules once daily or a 5-10-day regimen of co-amoxiclav, one 625 mg tablet three times daily.
- Azithromycin produced a significantly higher cure rate (70.6% versus 61.1%) than co-amoxiclav (P = 0.011) and there were fewer failures (7.8% versus 13.6%) and relapses in the azithromycin-treated group, giving a higher overall response rate for azithromycin (89.7% versus 80.2%, P = 0.0003).
With azithromycin, compliance was better than with co-amoxiclav and there was a significantly shorter time to improvement or cure. A higher incidence of adverse events, mostly gastrointestinal, was reported by patients taking co-amoxiclav (21.3% versus 14%, P = 0.0097), causing more patients in this group to discontinue therapy (7% versus 1.2%, P = 0.00004).
Is AMOX CLAV stronger than penicillin?
Penicillins are a class of antibiotics used against a wide range of bacteria. Both penicillin and amoxicillin are penicillin-class drugs. While the medicines penicillin V and penicillin G are naturally occurring penicillins, amoxicillin was made by chemically modifying penicillins to make them more powerful.
What is the strongest antibiotic to take?
Vancomycin 3.0 is one of the most potent antibiotics ever created.