How To Increase Insulin In Body?


How To Increase Insulin In Body
6. Add more colorful fruit and vegetables to your diet – Not only are fruits and vegetables nutritious, they also provide powerful health-boosting effects. In particular, colorful fruits and vegetables are rich in plant compounds that have antioxidant properties ( 37 ).

Antioxidants bind to and neutralize molecules called free radicals, which can cause harmful inflammation throughout the body ( 38 ). Many studies have found that eating a diet rich in plant compounds is linked to higher insulin sensitivity ( 39, 40, 41, 42 ). When you’re including fruit in your diet, stick to normal portion sizes and limit your intake to one piece per sitting and no more than 2 servings per day.

Summary Colorful fruits and vegetables are rich in plant compounds that help increase insulin sensitivity. But be careful not to eat too much fruit in a single sitting, as some types are high in sugar.

What promotes insulin in the body?

How is insulin controlled? – The main actions that insulin has are to allow glucose to enter cells to be used as energy and to maintain the amount of glucose found in the bloodstream within normal levels. The release of insulin is tightly regulated in healthy people in order to balance food intake and the metabolic needs of the body.

This is a complex process and other hormones found in the and pancreas also contribute to this blood glucose regulation. When we eat food, glucose is from our gut into the bloodstream, raising blood glucose levels. This rise in blood glucose causes insulin to be released from the pancreas so glucose can move inside the cells and be used.

As glucose moves inside the cells, the amount of glucose in the bloodstream returns to normal and insulin release slows down. Proteins in food and other hormones produced by the gut in response to food also stimulate insulin release. Hormones released in times of stress, such as adrenaline, stop the release of insulin, leading to higher blood glucose levels to help cope with the stressful event.

What causes poor insulin?

What causes insulin resistance? – Scientists still have a lot to discover about how exactly insulin resistance develops. So far, they’ve identified several genes that make a person more or less likely to develop insulin resistance. In addition, older people are more prone to insulin resistance.

Does coffee spike insulin?

4. Discussion – This meta-analysis evaluated the effects of coffee consumption on HOMA-IR and Matsuda index by analyzing four RCTs. HOMA-IR is used in many studies as a tool for evaluating insulin resistance and mainly reflects liver insulin resistance, This index was more reliable to assess insulin resistance than the fasting glucose/insulin ratio and was an independent predictor of cardiovascular disease, Matsuda index is a simple index of whole-body insulin sensitivity including liver and muscle, Other surrogate indices, except for HOMA-IR and Matsuda, were rarely used in coffee studies. Although not included in the search terms, insulin resistance indices using C-peptide levels (e.g., clamp-like index (CLIX), C-peptide immunoreactivity insulin resistance (CPR-IR)) exist, However, these indices have not been used previously to assess the effects of coffee. A previous meta-analysis reported no significant effect of coffee consumption on HOMA-IR relative to the control by analyzing two RCTs, Our study, which analyzed two more studies, showed that coffee consumption significantly decreased HOMA-IR. However, the robustness of the result was not warranted. The significance of our result was driven by one significant result from a large-weighted study. The weight of the crossover design is generally larger than that of parallel design in a meta-analysis, The characteristics of the group showing significant results were different from those of other studies. They were young adults (aged 18–45 years), had a normal weight (BMI < 25 kg/m 2 ), and did not have any metabolic syndrome including hypercholesterolemia. In such a population, the possibility of coffee consumption lowering insulin resistance cannot be ruled out. However, it is difficult to conclude that coffee consumption reduces insulin resistance from one study. Moreover, coffee consumption did not significantly affect the Matsuda index. Although not included in this meta-analysis, in one non-RCT, HOMA-IR was 3.93, 4.10, and 4.22 in subgroups that consumed zero, four, and eight cups of coffee daily, respectively, The difference was not significant, and other markers of glucose metabolism also were not significantly different, Some studies reported HOMA for β-cell function (HOMA-B) as an indicator of insulin resistance. There was no significant difference in HOMA-B between the coffee consumption and placebo groups in a study by Alperet et al., Mansour et al. conducted an RCT that administered two main coffee components, caffeine and chlorogenic acid, to patients with non-alcoholic fatty liver disease and type 2 diabetes, HOMA-IR between chlorogenic acid plus caffeine, chlorogenic acid, caffeine, and placebo did not differ significantly, Previous studies showed that caffeine can lower insulin sensitivity and increase insulin resistance and glucose concentration, MacKenzie et al. conducted a randomized crossover trial and found that 400 mg of caffeine (equivalent to two cups of coffee) per day decreases insulin sensitivity in young adults, The mechanism of caffeine's effects on glucose metabolism has not been fully revealed, but several have been suggested. Caffeine inhibits glucose uptake and glycogen synthase activity in the skeletal muscle by competitively blocking adenosine receptors, Other mechanisms include increased levels of epinephrine and free fatty acids that can increase insulin resistance after caffeine intake, However, the nonsignificant effects of coffee on insulin resistance and sensitivity in the present meta-analysis might be due to other ingredients in coffee that may negate the effects of caffeine on insulin resistance and sensitivity, Chlorogenic acid reduced glucose concentrations, and its metabolite, quinides, increased insulin sensitivity in rats, Chlorogenic acid may competitively inhibit glucose absorption in the intestine and reduce hepatic glucose output through glucose-6-phosphatase inhibition, This study has several limitations. First, the effects of coffee consumption for more than 24 weeks were not evaluated. This is a limitation of RCTs compared to epidemiologic studies, but a controlled setting (e.g., pre-defined coffee intake, randomly assigned participants) reduces bias and outweighs the disadvantages of an RCT design. Second, the small number of studies limited the evaluation of effect size according to the amount of coffee consumption or caffeine content and the characteristics of the participants through meta-regression. Since coffee is widely consumed and caffeine is addictive, it is difficult to conduct RCTs controlling coffee consumption. Moreover, controlling several confounding variables that affect glucose metabolism (e.g., diet composition and exercise) is difficult. Third, there was heterogeneity in study designs (parallel and crossover). Some researchers recommend combining the results for each research design, which was not done in this meta-analysis due to the small number of included studies.

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What triggers insulin the most?

How Secreted Insulin Works in Your Body Medically Reviewed by on April 11, 2023 Insulin is a hormone that helps control your body’s blood sugar level and metabolism – the process that turns the food you eat into energy. Your pancreas makes insulin and releases it into your bloodstream. Insulin helps your body use sugar for the energy it needs, and then store the rest.

  • After you eat, your intestines break down carbohydrates from food into glucose, a type of sugar.
  • That glucose goes into your bloodstream, which makes your blood sugar level rise.
  • Your pancreas is an organ that sits just behind your stomach.
  • It releases insulin to control the level of glucose in your blood.

Your body makes and releases insulin in a feedback loop based on your blood sugar level. At its most basic level, it’s similar to your home’s heating and cooling system, which releases cool or warm air as the temperatures rise or fall. High blood sugar stimulates clusters of special cells, called beta cells, in your pancreas to release insulin.

The more glucose you have in your blood, the more insulin your pancreas releases. Insulin helps move glucose into cells. Your cells use glucose for energy. Your body stores any extra sugar in your liver, muscles, and fat cells. Once glucose moves into your cells, your blood sugar level goes back to normal.

Low blood sugar prompts a different cluster of cells in your pancreas to release another hormone called glucagon. Glucagon makes your liver break down the stored sugar, known as glycogen, and release it into your bloodstream. Insulin and glucagon alternate their release throughout the day to keep your blood sugar levels steady.

This system works well when you have a healthy pancreas, but it can break down if you get diabetes. There are two main types of diabetes: Type 1 diabetes is an autoimmune disease that often starts in childhood. Your immune system attacks and destroys beta cells in the pancreas that make insulin. Type 2 diabetes can affect adults or children.

It’s a progressive disease, meaning that it happens over time. Your pancreas will develop problems releasing insulin. Eventually, this form of diabetes will also make it harder for your cells to use insulin, which is called insulin resistance. Type 2 diabetes is more common in people who are overweight or obese.

In both types of diabetes, blood sugar rises. Having high blood sugar for a long period of time can damage blood vessels and organs like your eyes, heart, and kidneys. Because your body can’t use glucose properly for energy, diabetes can make you feel very tired. Women can also get diabetes when they’re pregnant.

That’s called gestational diabetes. You may also have heard of prediabetes and insulin resistance, which can lead to type 2 diabetes (though it’s not too late to stop that from happening through lifestyle change). Until the early 20th century, the only way to treat type 1 diabetes was with a strict low-carbohydrate, low-calorie diet.

  1. In 1921, Canadian surgeon Frederick Banting and his assistant Charles Best discovered insulin.
  2. The introduction of insulin as a treatment changed the outlook for people with this disease.
  3. Today, people with type 1 diabetes and some with type 2 diabetes need to take insulin every day to keep their blood sugar levels steady.

Getting your blood sugar levels back to normal helps prevent diabetes complications. © 2023 WebMD, LLC. All rights reserved. : How Secreted Insulin Works in Your Body

Can insulin be increased naturally?

– Sticking to a heart-healthy and balanced diet and regularly moving your body can usually help manage blood glucose levels. These lifestyle changes are especially helpful in complementing medical treatment. If you have either type of diabetes, you should make some simple changes to your diet, including:

eating more fruits, vegetables, and whole grainsreducing your intake of processed foods and added sugarconsuming lean, protein-rich foods, like chicken, fish, and plant-based proteins

Some doctors may recommend that people with diabetes count carbohydrates to better manage their blood sugar. In these cases, it may be helpful to meet regularly with a registered dietitian to make sure you’re staying on track and getting the nutrients you need. There are other ways to help manage type 1 diabetes other than dietary changes, including:

exercising regularlymaintaining a moderate weightavoiding or quitting smokingmanaging triglyceride levels managing high HDL cholesterol levels

What happens if insulin is low?

What is an insulin in blood test? – This test measures the amount of insulin in your blood. Insulin is a hormone that helps move blood sugar, known as glucose, from your bloodstream into your cells. Glucose comes from the foods you eat and drink. It is your body’s main source of energy.

  • Hyperglycemia, blood glucose levels that are too high. It happens when your body doesn’t make enough insulin. If there’s not enough insulin, glucose can’t get into your cells. It stays in the bloodstream instead.
  • Hypoglycemia, blood glucose levels that are too low. If your body sends too much insulin into the blood, too much glucose will go into your cells. This leaves less in the bloodstream.

Diabetes is the most common cause of abnormal glucose levels. There are two types of diabetes,

  • Type 1 Diabetes, If you have type 1 diabetes, your body makes little or no insulin at all. This can cause hyperglycemia.
  • Type 2 Diabetes, If you have type 2 diabetes, your body may still be able to make insulin, but the cells in your body don’t respond well to insulin and can’t easily take up enough glucose from your blood. This is called insulin resistance,

Insulin resistance often develops before type 2 diabetes. At first, insulin resistance causes the body to make extra insulin, to make up for ineffective insulin. Extra insulin in the bloodstream can cause hypoglycemia. But insulin resistance tends to get worse over time.

What is a natural source of insulin?

We hardly think of pancreas as an important endocrine organ unless it starts to create a problem. Pancreas has two important roles to play: a) Make insulin for blood sugar control. b) Create enzymes for the metabolism of fats and proteins. Malfunction of pancreas could result in a variety of problems – the most common being diabetes.

  • Fortunately, nature has given us some foods that boost the beta cells of pancreas to produce insulin and help alleviate diabetes, of course, coupled with right lifestyle changes.
  • Red cabbage Cabbage, especially red, is a boon for cancer and diabetes patients.
  • The natural red pigments of red cabbage, betalains, helps lower blood sugar levels and boosts insulin production.

Lady’s finger/okra Packed with dietary fibre, it helps in stabilising blood sugar levels, and aids in enhancing production of insulin as well as its increased secretion. Also, their seeds are full of alpha-glucosidase inhibitors that prevent starches from converting to glucose.

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One can slice okra pods, soak in water overnight and can consume the water next day. Bittergourd/Bitter melon Also known as karela, it may taste quite bitter but has the capacity to stimulate pancreas (an action perhaps similar to that of sulfonylurea drugs). This property can be attributed to the three substances these veggies contain: charantin, vicine and a polypeptide-p.

Bittermelon tea, juice or a curry preparation are some ways to consume it. A cup of fresh bitter gourd juice mixed with 1 tbsp amla juice (gooseberry) can enable natural insulin secretion. Fenugreek seeds Fenugreek is widely known and used, but it’s the seeds that contain trigonelline, a plant alkaloid known to reduce blood sugar levels.

They can be used in various forms – like a powder of fenugreek seeds soaked in hot water to reduce your rising blood sugar levels, overnight soaked and sprouted seeds can be added to salads or idli/dosa batter. Curcumin Turmeric extracts are known to act directly on pancreatic beta cells to help produce insulin normally, by inhibiting phosphodiesterase activity.

Cinnamon (Srilankan) This barky spice not only makes cells sensitive to insulin but also works similar to natural insulin produced by our pancreas. Sprinkle some cinnamon in your meals, tea, or try a cinnamon supplement. Disclaimer: Before trying any remedy, it’s advisable to bring it to your doctor’s notice – as certain foods can interact with the medications Insulin plant (Jarul) Okay, so here’s the most interesting food.

As the name suggests, this plant — commonly-grown in South India — helps in boosting insulin production naturally by activating beta cells of pancreas. The corosolic acid present in the leaves induces insulin production and thus controls hyperglycaemia in the blood. That’s not all, it’s also hypolipidemic, diuretic, antioxidant, anti-microbial and anti-cancerous.

Chew 1-2 leaves every morning. Other foods like flaxseeds, grapes, aloevera gel juice, are also known to repair beta cells and help in insulin production naturally. By Luke Coutinho MD, alternative medicine

What kills insulin producing cells?

A microscopic image taken from the pancreas of a T1D donor (top) and Control donor (bottom) displaying HLA-DR+ cytokeratin+ cells labeled by immunofluorescence (IF), a technique for determining the location of an antibody in tissues by reaction with an antibody labeled with a fluorescent dye.

PHILADELPHIA— For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

This study is published today in Nature Metabolism, “The first events that occur in a patient heading towards Type 1 Diabetes, the events that trigger autoimmunity, have been difficult for researchers to pin down because of our inability to biopsy the pancreas, and the fact that clinical diagnosis is only made once massive beta cell destruction has occurred,” said senior author Golnaz Vahedi, PhD, an associate professor of Genetics and member of the Institute for Diabetes, Obesity and Metabolism at the Perelman School of Medicine at the University of Pennsylvania.

That is why it is so important to develop a better understanding of the earliest molecular events in T1D pathogenesis, so we can uncover more about biomarker identification and disease prevention.” Autoimmune diseases, which affect as many as 23.5 million Americans, occur when the body’s immune system attacks and destroys healthy organs, tissues and cells.

There are more than 80 types of autoimmune diseases, including rheumatoid arthritis, inflammatory bowel disease, and T1D. In T1D, immune cells called T lymphocytes attack and destroy insulin-secreting pancreatic beta cells and the pancreas stops producing insulin, the hormone that controls blood sugar levels.

“Although it might be an ultimately unsuccessful attempt of the pancreas to limit the adaptive T cell response responsible for destroying beta cells, this finding that the ductal cells are capable of playing this suppressive role towards autoimmune T cell responses is unprecedented,” said co-senior author Klaus Kaestner, PhD, the Thomas and Evelyn Suor Butterworth Professor in Genetics.

“Our study shows that these cells, which had never previously been linked to immunity, may change themselves to protect the pancreas.” Established in 2016, the Human Pancreas Analysis Program (HPAP) is supported by a $28 million grant from the National Institutes of Health with major contributions from Penn, the University of Florida and Vanderbilt University.

The HPAP, which is co-directed by Kaestner and Ali Naji MD, PhD, the J. William White Professor of Surgical Research, started collecting pancreatic tissues from hundreds of deceased organ donors diagnosed with T1D. Because many T1D patients harbor beta cell autoantibodies called Glutamic Acid Decarboxylase (GAD) in their bloodstream years before clinical diagnosis, HPAP also collects samples from autoantibody-positive donors, who are at risk for developing T1D but have not received that diagnosis.

“Our study took those quality tissue samples and created high-resolution measurements of millions of cells from patients at various stages of T1D progression, resulting in a single-cell atlas of pancreatic islets,” said co-senior author R. Babak Faryabi, PhD, an assistant professor of Pathology and Laboratory Medicine and a core member of Epigenetics Institute at Penn.

Blood tests to check for levels of GAD are common for patients with, or at risk for, T1D, and doctors use it as a diagnostic tool. Another finding of this study is the new understanding of what is happening on a molecular level in the pancreas and how it correlates to the findings of the GAD test. “Our study is the first to show that even when a person is not clinically considered to have T1D, high levels detected in their GAD test indicate large-scale transcriptional remodeling of their beta cells,” said Naji, a study co-senior author.

“It solidifies to clinicians to closely monitor patients with increasing levels of GAD, as we now know what cellular and molecular changes are in motion in relation to those levels.” Although researchers do not yet know whether these transcriptional changes are contributing to or are consequences of disease pathogenesis, the discovery of molecular phenotypic changes in pancreatic cells of autoantibody-positive individuals advances the understanding of early pancreatic changes occurring in T1D, and sets the course for continued research in this area.

This research was funded by grants through the National Institutes of Health (UC4 DK112217, U01DK112217, R01CA230800, R01HL145754, and U01DK127768). Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care.

Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation’s first medical school) and the University of Pennsylvania Health System, which together form a $9.9 billion enterprise.

The Perelman School of Medicine has been ranked among the top medical schools in the United States for more than 20 years, according to U.S. News & World Report’s survey of research-oriented medical schools. The School is consistently among the nation’s top recipients of funding from the National Institutes of Health, with $546 million awarded in the 2021 fiscal year.

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The University of Pennsylvania Health System’s patient care facilities include: the Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center—which are recognized as one of the nation’s top “Honor Roll” hospitals by U.S. News & World Report—Chester County Hospital; Lancaster General Health; Penn Medicine Princeton Health; and Pennsylvania Hospital, the nation’s first hospital, founded in 1751.

Additional facilities and enterprises include Good Shepherd Penn Partners, Penn Medicine at Home, Lancaster Behavioral Health Hospital, and Princeton House Behavioral Health, among others. Penn Medicine is powered by a talented and dedicated workforce of more than 47,000 people. The organization also has alliances with top community health systems across both Southeastern Pennsylvania and Southern New Jersey, creating more options for patients no matter where they live.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2021, Penn Medicine provided more than $619 million to benefit our community.

How do you know if you are insulin deficiency?

Diagnosing Insulin Resistance – Doctors don’t usually test people for insulin resistance, according to the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK), a division of the National Institutes of Health (NIH). The best testing method for insulin resistance is complicated and used mainly in research, the NIDDK says.

What illness is lack of insulin?

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.

Does green tea spike insulin?

– But tea’s benefits don’t stop at prevention. For people already diagnosed with diabetes, green tea may be able to help manage blood sugar levels. According to a comprehensive review, green tea consumption is associated with decreased fasting glucose levels and A1C levels, as well as reduced fasting insulin levels, which are a measurement of diabetes health.

Does honey spike insulin?

Table 1 – Preclinical studies on animal models regarding the effect of honey on induced diabetes mellitus.

Ref. Animal models Applied treatment Obtained results
60 diabetic rats divided into 6 groups: (1) distilled water, (2) honey, (3) glibenclamide, (4) glibenclamide and honey, (5) metformin, and (6) metformin and honey Distilled water, honey, glibenclamide, glibenclamide and honey, and metformin or metformin and honey treatment orally once a day for 4 weeks Honey significantly increased insulin (0.41 ± 0.06 ng/ml), decreased hyperglycemia (12.3 ± 3.1 mmol/L), and fructosamine (304.5 ± 10.1  μ mol/L). Glibenclamide and metformin alone significantly reduced hyperglycemia, but combined with honey, produced significantly much lower blood glucose (8.8 ± 2.9 or 9.9 ± 3.3 mmol/L, resp.) compared to glibenclamide or metformin alone (13.9 ± 3.4 or 13.2 ± 2.9 mmol/L).

Does salt spike insulin?

Reduce your risk – Although salt does not affect blood glucose levels, it’s important to limit the amount you eat as part of your diabetes management because too much salt can raise your blood pressure. People with diabetes are more likely to be affected by high blood pressure, which increases the risk of heart disease, stroke and kidney disease.

Do eggs raise insulin levels?

Conclusion – Intake of egg-based breakfast meals (12 eggs/week), compared with consumption of non-egg, higher-CHO breakfast meals, did not adversely affect insulin sensitivity and other aspects of CHO homeostasis. LDL-C declined less from baseline (−2.9%) during the Egg condition than during the Non-Egg condition (−6.0%), while systolic blood pressure was reduced by 2.7% during the Egg condition and was unchanged during the Non-Egg condition.

HOMA-IR was lower by a net difference of 23% during the Egg condition than the Non-Egg condition, but smaller and nonsignificant differences were observed for other indices of insulin sensitivity. No other significant differences were observed in the cardiometabolic risk-factor profile. Of interest, egg intake at the breakfast meal was associated with increased reported daily energy intake from non-study foods but was not associated with increased body weight.

Additional research appears warranted to confirm this finding and investigate mechanistic explanations.

Does protein raise insulin?

Dietary proteins have an insulinotropic effect and thus promote insulin secretion, which indeed leads to enhanced glucose clearance from the blood. In the long term, however, a high dietary protein intake is associated with an increased risk of type 2 diabetes.

How can I check my insulin level at home?

How to test your blood sugar – Blood sugar testing requires the use of a blood sugar meter. The meter measures the amount of sugar in a small sample of blood, usually from your fingertip, that you place on a disposable test strip. Even if you use a CGM, you’ll still need a blood sugar meter to calibrate your CGM device daily.

  1. Wash and dry your hands well. (Food and other substances can give you an inaccurate reading.)
  2. Insert a test strip into your meter.
  3. Prick the side of your fingertip with the needle (lancet) provided with your test kit.
  4. Touch and hold the edge of the test strip to the drop of blood.
  5. The meter will display your blood sugar level on a screen after a few seconds.

Some meters can test blood taken from an alternate site, such as the forearm or palm. But these readings may not be as accurate as readings from the fingertips, especially after a meal or during exercise, when blood sugar levels change more frequently. Alternate sites aren’t recommended for use in calibrating CGMs,

What foods to avoid to lower insulin?

9. Foods to avoid for insulin resistance – If you’re managing insulin resistance through what you eat, it’s important to cut down on processed foods with added sugar. Foods like these increase your risk of a blood sugar spike:

soda, juice, and sweet tea refined grains, including white rice, white bread, and cereal with added sugar ultra-processed snack foods like candy, cookies, cakes, and chips

Does banana spike insulin?

How many calories are there in a banana? – A medium banana has 105 calories and 27 grams of carbohydrate. Not much more than many other types of fruit: 1 medium pear (103 calories, 27 gm carb), 1 medium apple (95 calories, 25 gm carb), 1 cup pineapple (82 calories, 21 gm carb) and 1 cup blueberries (84 calories, 21 gm carb).

Or maybe bananas are maligned because they’re believed to have high glycemic index (GI), causing your blood sugar and insulin to spike quickly after eating one. False, again. Bananas are actually low on the GI scale, having a glycemic index value of 51. (Foods with a low GI cause your blood sugar to rise gradually, not quickly, after eating them.

GI values less than 55 are considered low.) So I have to disagree with your trainer.

Does protein raise insulin levels?

Dietary proteins have an insulinotropic effect and thus promote insulin secretion, which indeed leads to enhanced glucose clearance from the blood. In the long term, however, a high dietary protein intake is associated with an increased risk of type 2 diabetes.

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